Biološki učinci vina: utjecaj vinifikacijske tehnologije, dealkoholizacije i starenja vina

Opis projekta
Grape production technology and procedures in wine making and processing significantly affect biochemical composition and organoleptic properties of wine. However, the effects of different enological procedures on biological activity of wine are poorly investigated. The overall aim of this project, which represents an interdisciplinary research effort of experts from fields of biotechnology and biomedicine, is to investigate how different enological procedures in wine making (changes of maceration time, partial/complete dealcoholization, aging of wine) may affect its biological activity. This also includes investigation of potential differences in distinctive biological effects between wines obtained by the technology of white and red wine production. In contrast to the process of red wine production, in the white wine production there is no maceration in contact with grape seeds and skins, and only fermentation of immediately separated grape juice occurs. So, biological potentials of white wines may considerably differ from that of red wines. Conversely, if even short maceration is allowed in the process of white wine making, polyphenolic content and antioxidant potential of such wines is significantly enhanced. There are several studies demonstrating superior effects of red versus white wine on certain cardiovascular parameters. However, epidemiological evidence demonstrating specific benefits of red over white wine is poor and conclusive studies comparing the two are missing. Detailed biochemical analyses of all test wines will be performed and their biochemical properties will be correlated with their biological activity. Among numerous biological effects of wine and its constituents, this project focuses on cardiovascular, antioxidative, anti-inflammatory and antibacterial effects of wine that will be examined on a spectrum of in vitro and in vivo biological systems including small laboratory animals and human volunteers.


Šifra projekta


Vrsta projekta

Vrsta financiranja
Kompetitivno projektno financiranje

HRZZ - Hrvatska zaklada za znanost

Detalji financiranja
 IP - Istraživački projekti

Ukupan iznos financiranja projekta
998.070,00 HRK

Trajanje projekta
2014-09-01 - 2018-08-31

Ustanova - uloga
Medicinski fakultet, Split - Nositelj (998.070,00 HRK)

Osoba - Ustanova - uloga [pocetak - zavrsetak]
Mladen Boban (MBZ: 207836, CROSBI: 15610) - nema - Voditelj projekta [2014-09-01 - 2018-08-31]